Retigabine-d4 Dihydrochloride

Retigabine-d4 Dihydrochloride - Names and Identifiers

Name	Retigabine-d4 Dihydrochloride
Synonyms	D 20443-d4 Retigabine-d4 Dihydrochloride Ethyl [2-AMino-4-[[(4-fluorophenyl-d4)Methyl]aMino]phenyl]carbaMate Dihydrochloride N-[2-AMino-4-[4-(fluorobenzyl-d4)aMino]phenyl]carbaMic Acid Ethyl Ester Dihydrochloride 1,1,2,2,2-pentadeuterioethyl N-[2-amino-4-[(4-fluorophenyl)methylamino]phenyl]carbamate
CAS	1285886-70-5

Retigabine-d4 Dihydrochloride - Physico-chemical Properties

Molecular Formula	C16H18FN3O2
Molar Mass	303.3314232
Melting Point	>183°C (dec.)
Solubility	DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Appearance	Solid
Color	White to Off-White
Storage Condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Stability	Hygroscopic

Retigabine-d4 Dihydrochloride - Introduction

Retigabine-d4 dihydroxychloride (Retigabine-d4 dihydroxychloride) is a specially marked antiepileptic drug, also known as Retigabine-d4 HCl. Its chemical formula is C11H8D4Cl2N. Retigabine-d4 Dihydrochloride is obtained by the reaction of deuterated benzamide and 3,4-difluorophenylacetic acid. It is a white solid powder.

The main use of Retigabine-d4 Dihydrochloride is as a standard substance in the field of research and quality control. It is mainly used for the preparation of anti-epileptic drug calibration curve, mass spectrometry analysis and other related experiments.

The preparation method of Retigabine-d4 Dihydrochloride generally adopts organic synthetic chemical method. First, The deuterated benzamide is reacted with 3,4-difluorophenylacetic acid in a suitable solvent, and then the obtained product is purified by crystallization and dried, and finally the Retigabine-d4 Dihydrochloride is obtained.

Regarding safety information, the toxicity and safety of Retigabine-d4 Dihydrochloride have not been fully established. Therefore, it is necessary to take necessary safety measures when using, such as wearing gloves, goggles and protective clothing. In addition, it should be stored in a dry, cool place, and avoid contact with strong oxidants, strong acids and strong bases. In case of accidental inhalation, contact or ingestion, medical attention should be sought immediately.

In General, Retigabine-d4 Dihydrochloride is an antiepileptic drug used for research and quality control, and its preparation method is prepared by organic synthesis reaction. Pay attention to safety protection when using, and properly stored.

Last Update：2024-04-09 20:52:54